| 產品編號 | bs-5083R-BF647 |
| 英文名稱 | Rabbit Anti-MTTP/BF647 Conjugated antibody |
| 中文名稱 | BF647標記的微粒體甘油三酯轉運蛋白 |
| 別 名 | ABL; Microsomal triglyceride transfer protein (large polypeptide 88kDa); Microsomal triglyceride transfer protein 88kD; Microsomal triglyceride transfer protein; Microsomal triglyceride transfer protein large subunit; MTP; MTP large subunit; MTP_HUMAN; MTTP; Transfer RNA, mitochondrial, proline; tRNA-Pro, mitochondrial; Microsomal triglyceride transfer protein large; Microsomal triglyceride transfer protein large Precursor; microsomal triglyceride transfer protein large subunit precursor. |
| 規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
| 說 明 書 | 100ul |
| 研究領域 | 腫瘤 心血管 細胞生物 免疫學 信號轉導 脂蛋白 新陳代謝 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應 | (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Guinea Pig, ) |
| 產品應用 | IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 97kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human MTTP |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產品介紹 |
background: MTTP catalyzes the transport of triglyceride, cholesteryl ester, and phospholipid between phospholipid surfaces. MTTP is required for the secretion of plasma lipoproteins that contain apolipoprotein B. It is positively regulated by cholesterol and negatively regulated by insulin. Defects in MTP are the cause of abetalipoproteinemia. Function: Catalyzes the transport of triglyceride, cholesteryl ester, and phospholipid between phospholipid surfaces. Required for the secretion of plasma lipoproteins that contain apolipoprotein B. Subunit: Heterodimer composed of MTTP and of protein disulfide isomerase (P4HB/PDI) (By similarity). Subcellular Location: Endoplasmic reticulum. Tissue Specificity: Liver and small intestine. Also found in ovary, testis and kidney. DISEASE: Abetalipoproteinemia (ABL) [MIM:200100]: An autosomal recessive disorder of lipoprotein metabolism. Affected individuals produce virtually no circulating apolipoprotein B-containing lipoproteins (chylomicrons, VLDL, LDL, lipoprotein(A)). Malabsorption of the antioxidant vitamin E occurs, leading to spinocerebellar and retinal degeneration. Note=The disease is caused by mutations affecting the gene represented in this entry. Similarity: Contains 1 vitellogenin domain. Database links: Entrez Gene: 100734244 Guinea pig Entrez Gene: 100053803, Horse Entrez Gene: 4547 Human Entrez Gene: 17777 Mouse Entrez Gene: 100341961 Rabbit Omim: 590075 Human SwissProt: P55157 Human SwissProt: O08601 Mouse Unigene: 195799 Human Unigene: 2941 Mouse Unigene: 81556 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 微粒體甘油三酯轉移蛋白（microsomal triglyceride transfer protein，MTP）是一種主要分布于肝細胞、腸上皮細胞中的脂質轉移蛋白，存在于細胞微粒體、內質網腔內，在內質網內含量最高，占總蛋白的0．5％-1．0％,MTTP在甘油三酯轉運及極低密度脂蛋白組裝和分泌中發(fā)揮著重要作用。 |
| 1、抗體溶解方法 | |
| 2、抗體修復方式 | |
| 3、常用試劑的配制 | |
| 4、免疫組化操作步驟 | |
| 5、免疫組化問題解答 | |
| 6、Western Blotting 操作步驟 | |
| 7、Western Blotting 問題解答 | |
| 8、關于肽鏈的設計 | |
| 9、多肽的溶解與保存 | |
| 10、酶標抗體效價測定程序 | |
