亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
国产午夜人做人免费视频APP,国产对白国语对白,18禁止看的免费污网站
Rabbit Anti-CD171/L1CAM/FITC Conjugated antibody (bs-1996R-FITC)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-1996R-FITC
英文名稱 Rabbit Anti-CD171/L1CAM/FITC Conjugated antibody
中文名稱 FITC標(biāo)記的神經(jīng)細(xì)胞粘附分子配體1抗體
別    名 Antigen identified by monoclonal; R1; CAML1; CD171; CD171 antigen; HSAS; HSAS1; Hyd; L1; L1 cell adhesion molecule; L1-NCAM; L1cam; L1CAM_HUMAN; MASA; MIC5; N CAML1; N-CAM-L1; NCAM-L1; NCAM-L1; NCAML1; Nerve-growth factor-inducible large external glycoprotein; Neural cell adhesion molecule L1; NILE; OTTHUMP00000025992; S10; SPG1.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 發(fā)育生物學(xué)  神經(jīng)生物學(xué)  信號轉(zhuǎn)導(dǎo)  生長因子和激素  細(xì)胞骨架  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, )
產(chǎn)品應(yīng)用 Flow-Cyt=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 138kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CD171
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
L1cam (L1 cell adhesion molecule isoform 1 precursor) is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of a neuron-specific exon is thought to be functionally relevant. [provided by RefSeq].

Function:
Cell adhesion molecule with an important role in the development of the nervous system. Involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. Binds to axonin on neurons.

Subcellular Location:
Cell membrane; Single-pass type I membrane protein.

DISEASE:
Defects in L1CAM are the cause of hydrocephalus due to stenosis of the aqueduct of Sylvius (HSAS) [MIM:307000]. Hydrocephalus is a condition in which abnormal accumulation of cerebrospinal fluid in the brain causes increased intracranial pressure inside the skull. This is usually due to blockage of cerebrospinal fluid outflow in the brain ventricles or in the subarachnoid space at the base of the brain. In children is typically characterized by enlargement of the head, prominence of the forehead, brain atrophy, mental deterioration, and convulsions. In adults the syndrome includes incontinence, imbalance, and dementia. HSAS is characterized by mental retardation and enlarged brain ventricles.
Defects in L1CAM are the cause of mental retardation-aphasia-shuffling gait-adducted thumbs syndrome (MASA) [MIM:303350]; also known as corpus callosum hypoplasia, psychomotor retardation, adducted thumbs, spastic paraparesis, and hydrocephalus or CRASH syndrome. MASA is an X-linked recessive syndrome with a highly variable clinical spectrum. Main clinical features include spasticity and hyperreflexia of lower limbs, shuffling gait, mental retardation, aphasia and adducted thumbs. The features of spasticity have been referred to as complicated spastic paraplegia type 1 (SPG1). Some patients manifest corpus callosum hypoplasia and hydrocephalus. Inter- and intrafamilial variability is very wide, such that patients with hydrocephalus, MASA, SPG1, and agenesis of corpus callosum can be present within the same family.
Defects in L1CAM are the cause of spastic paraplegia X-linked type 1 (SPG1) [MIM:303350]. Spastic paraplegia is a degenerative spinal cord disorder characterized by a slow, gradual, progressive weakness and spasticity of the lower limbs.
Note=Defects in L1CAM may contribute to Hirschsprung disease by modifying the effects of Hirschsprung disease-associated genes to cause intestinal aganglionosis.
Defects in L1CAM are a cause of partial agenesis of the corpus callosum (ACCPX) [MIM:304100]. A syndrome characterized by partial corpus callosum agenesis, hypoplasia of inferior vermis and cerebellum, mental retardation, seizures and spasticity. Other features include microcephaly, unusual facies, and Hirschsprung disease in some patients.

Similarity:
Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.
Contains 5 fibronectin type-III domains.
Contains 6 Ig-like C2-type (immunoglobulin-like) domains.

Database links:

Entrez Gene: 3897 Human

Entrez Gene: 16728 Mouse

Entrez Gene: 50687 Rat

Omim: 308840 Human

SwissProt: P32004 Human

SwissProt: P11627 Mouse

SwissProt: Q05695 Rat

Unigene: 522818 Human

Unigene: 260568 Mouse

Unigene: 10378 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

NCAM-L1又稱L1細(xì)胞粘附分子(L1CAM)是一種細(xì)胞表面糖蛋白,屬于免疫球蛋白超家族的神經(jīng)細(xì)胞粘附分子家族。L1CAM可能在神經(jīng)系統(tǒng)發(fā)育過程中發(fā)揮作用。
版權(quán)所有 2004-2026 a6308.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
国产日产亚洲系列最新美使用方法 | 爽死你个放荡粗暴小淫货漫画 | 亚洲中文字幕在线观看 | 色欲久久精品亚洲AV无码一区 | 麻豆精品久久久一区二区 | 寡妇高潮一级毛片免费看 | 国产一区在线观看免费 | 91久久精品日日躁夜夜躁欧美 | 久久99免费视频 | 一个人免费观看视频www | 国产精品乱码一区二区三区 | 无码国产精品一区二区免费16 | 一级成人欧美一区在线观看 | ▓成人榴莲视频▓无码免费 | 女人高潮内射99精品 | 内射成人影片在线播放 | 久久久SS麻豆欧美国产日韩 | 成人免费看WWW网址入口 | 日本丰满护士BBW | 96在线看片免费视频国产 | 宝贝儿乖我们继续H | 久久综合亚洲色hezyo国产 | 国产精品爱啪在线播放 | 琪琪精品视频在线观看 | 宝贝乖调教跪趴SM主人玩具HH | AV 无码 高潮+喷水 | 91精品国产麻豆国产自产在线 | 日本动态120秒免费 小宝极品内射国产在线 | 日本免费在线观看视频 | 色欲午夜无码久久久久久 | 把女人弄爽大黄A大片片 | 亚洲国产AAA毛片无费看 | 国产精品va在线观看浪潮 | 韩日AV无码片一区二区三区 | 国产成人精品电影在线观看 | 国产精品欧美激情第一页 | 欧美叉叉叉BBB网站 久久精品视频91 | 中文字幕人妻熟女人妻A片 亚洲AV成人一区二区三区在线看 | 欧美日韩激情综合一区二区不卡 | 久久丁香婷深爱五月天网 | 蜜臀色欲AV在线播放国产日韩 |