亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
51视频精品全部免费视频,森泽佳奈痴汉电车侵犯超短裙,日韩青草青草久热精品视频在线网站乱码
Rabbit Anti-S100B/Cy5 Conjugated antibody (bs-2015R-Cy5)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-2015R-Cy5
英文名稱 Rabbit Anti-S100B/Cy5 Conjugated antibody
中文名稱 Cy5標(biāo)記的S100B蛋白抗體
別    名 NEF; Protein S100 B; Protein S100-B; S 100 calcium binding protein beta chain; S 100 protein beta chain; S 100 protein beta subunit; S-100 protein beta chain; S-100 protein subunit beta; S100; S100 calcium binding protein B; S100 calcium binding protein beta (neural); S100 calcium binding protein beta chain; S100 calcium-binding protein B; S100 protein beta chain; S100B_HUMAN; S100beta.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 腫瘤  細胞生物  神經(jīng)生物學(xué)  細胞周期蛋白  細胞分化  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Rat,  (predicted: Human, Mouse, Chicken, Cow, Rabbit, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 10kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human S100B
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
S100 beta is a member of the S100 family of proteins containing 2 EF-hand calcium binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.

Function:
Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling.

Subunit:
Dimer of either two alpha chains, or two beta chains, or one alpha and one beta chain. The S100B dimer binds two molecules of STK38 (By similarity). The S100B dimer interacts with two molecules of CAPZA1.

Subcellular Location:
Cytoplasm. Nucleus.

Tissue Specificity:
Although predominant among the water-soluble brain proteins, S100 is also found in a variety of other tissues.

Similarity:
Belongs to the S-101 family.
Contains 2 EF-hand domains.

Database links:

Entrez Gene: 6285 Human

Entrez Gene: 20203 Mouse

Entrez Gene: 25742 Rat

Omim: 176990 Human

SwissProt: P04271 Human

SwissProt: P50114 Mouse

SwissProt: P04631 Rat

Unigene: 422181 Human

Unigene: 235998 Mouse

Unigene: 8937 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

結(jié)構(gòu)蛋白(Structural Proteins)
S100B是一組可溶性、相對低分子質(zhì)量、高酸性蛋白,屬神經(jīng)膠質(zhì)細胞特異性蛋白,亦可存在于神經(jīng)纖維中。在研究腸神經(jīng)系統(tǒng)的形態(tài)特征及結(jié)構(gòu)特征中,S100B有良好的表達功能。
S100B蛋白其生理作用尚不清楚,可能與細胞內(nèi)鈣離子媒介的調(diào)節(jié)作用有關(guān)。S100B蛋白可存在于神經(jīng)鞘瘤,成軟骨細胞瘤、軟骨肉瘤、骨肉瘤、神經(jīng)膠質(zhì)瘤、郎格罕斯細胞瘤、一些癌腫和黑素細胞腫瘤等。
在免疫組化中,除了惡性黑素瘤皮損,S100B蛋白還在良性黑素細胞痣中增加,如:藍痣、普通后天痣、雀斑樣痣、Spitz痣、氣球狀細胞痣、色素性梭形細胞痣和發(fā)育不良痣中表達。還有報道S100B蛋白的染色強度與腫瘤細胞的黑素含量呈負相關(guān)。結(jié)締組織增生性的或親神經(jīng)的黑素瘤不易染色。
版權(quán)所有 2004-2026 a6308.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
免费少妇A级毛片野外大战 亚洲精品高清一二区久久 精品欧美一区二区三区成人片在线 | 亚洲AV成人一区二区三区在线看 | chengrenwangzhan免费观看 | 福利小视频在线播放 | 国产免费AV片在线播放唯爱网 | 亚洲国产精品特色大片观看完整版 | 好吊视频一区二区三区 | 欧美另类69xxxxx | 特级淫片aaaa毛片aa视频 | 中文字幕在线视频全部播放 | 黄片视频在线免费观看 | 日本人爽p大片免费看 | 国产一区二区精品久久岳 | 两口子交换真实刺激高潮 | 最近中文字幕在线中文视频 | 麻豆日产精品卡2卡3卡4卡5卡 | 国产女人18毛片水真多 | 欧美黑人又大又粗XXXXX视频 | 国产V综合V亚洲欧美久久 | 激情内射亚洲一区二区三区爱妻 | 亚洲第一成年人网站 | 太紧了夹得我的巴好爽欧美 | 美女脱18以下禁止看免费 | 爱剪辑视频社区在线资源 | 欧美精品一区二区三区 | 被三个男人绑着躁我好爽 | 特级无码一区二区三区毛片视频 | 久久99热狠狠色精品一区 | 超碰高清人人爽久久人人 | 久久香蕉综合一本到3atv | 国产欧美日韩一区二区三区 | 国内精品伊人久久久久 | 精品国产专区91在线 | 在线观看国产精品女主播 | 国产乱码一二三区精品 | 亚洲欧美日韩国产综合五月天 | 按摩媚药无码中文字幕 | 少妇裸体婬交视频免费看高清 | 99re热线精品视频 | 内射丰满高大五十五岁熟女 | 456亚洲人成在线播放网站 |