亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
国语对白露脸XXXXXX,最近免费中文字幕大全高清MV
Rabbit Anti-Bid/Biotin Conjugated antibody (bs-1153R-Bio)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-1153R-Bio
英文名稱 Rabbit Anti-Bid/Biotin Conjugated antibody
中文名稱 生物素標(biāo)記的BH3結(jié)構(gòu)域凋亡誘導(dǎo)蛋白抗體
別    名 Apoptic death agonist; Apoptotic death agonist; Apoptotic death agonist BID; BH3 interacting domain death agonist; BH3 interacting domain death agonist; BH3 interacting domain death agonist p11; BH3 interacting domain death agonist p13; BH3 interacting domain death agonist p15; BH3-interacting domain death agonist p11; BID; BID isoform ES(1b); BID isoform L(2); BID isoform Si6; BID_HUMAN; Desmocollin type 4; FP497; HGNC:1050; Human BID coding sequence; MGC15319; MGC42355; p11 BID; p13 BID; p15 BID; p22 BID.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 腫瘤  信號轉(zhuǎn)導(dǎo)  細(xì)胞凋亡  新陳代謝  線粒體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, 
產(chǎn)品應(yīng)用 WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 21kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Bid
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Bid, a BH3 domain containing proapoptotic Bcl2 family member, is localized in the cytosolic fraction of cells as an inactive precursor. Its active form is generated upon proteolytic cleavage by caspase 8 in the Fas signaling pathway. Cleaved Bid translocates to mitochondria and releases its potent proapoptotic activity, which in turn induces cytochrome c release and mitochondrial damage. The cytochrome c releasing activity of Bid was antagonized by Bcl2. Mutation in the SH3 domain can diminish the cytochrome c releasing activity. In animal model studies, Bid deficient mice are found resistant to the lethal effects of death factor signals relayed through Fas.

Function:
The major proteolytic product p15 BID allows the release of cytochrome c. Isoform 1, isoform 2 and isoform 4 induce ICE-like proteases and apoptosis. Isoform 3 does not induce apoptosis. Counters the protective effect of Bcl-2.

Subunit:
Forms heterodimers either with the pro-apoptotic protein BAX or the anti-apoptotic protein Bcl-2.

Subcellular Location:
Cytoplasm. Mitochondrion membrane. Note=When uncleaved, it is predominantly cytoplasmic. BH3-interacting domain death agonist p15: Mitochondrion membrane. Note=Translocates to mitochondria as an integral membrane protein. BH3-interacting domain death agonist p13: Mitochondrion membrane. Note=Associated with the mitochondrial membran. Isoform 1: Cytoplasm. Isoform 3: Cytoplasm. Isoform 2: Mitochondrion membrane. Note=A significant proportion of isoform 2 localizes to mitochondria, it may be cleaved constitutively.

Tissue Specificity:
Isoform 2 and isoform 3 are expressed in spleen, bone marrow, cerebral and cerebellar cortex. Isoform 2 is expressed in spleen, pancreas and placenta (at protein level). Isoform 3 is expressed in lung, pancreas and spleen (at protein level). Isoform 4 is expressed in lung and pancreas (at protein level).

Post-translational modifications:
TNF-alpha induces a caspase-mediated cleavage of p22 BID into a major p15 and minor p13 and p11 products.
Phosphorylated upon DNA damage, probably by ATM or ATR.

Database links:

Entrez Gene: 637 Human

Entrez Gene: 12122 Mouse

Entrez Gene: 64625 Rat

Omim: 601997 Human

SwissProt: P55957 Human

SwissProt: P70444 Mouse

SwissProt: Q9JLT6 Rat

Unigene: 591054 Human

Unigene: 235081 Mouse

Unigene: 31142 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 a6308.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
久久综合亚洲色hezyo国产 | 国产一级高清A片免费播 | 国产又粗又大又爽又免费视频 | 5278欧美一区二区三区 | 国产精品看片在线观看 | 久久人人做人人爽久久99国产乱子伦精品免 | 国产a级三级三级成人国产一级婬片 | 日本一卡二卡不卡视频查询 | 久久久精品天堂无码中文字幕 | 在线A亚洲老鸭窝天堂AV高清 | 99国产欧美久久久精品 | 亚洲中文字幕无码中文字无摸 | 国产成人精品久久综合 | 97人人爽人人爽爽人人一区二区 | 91资源在线播放 | 免费看男女下面日出水视频 | 狠狠的撞进去嗯啊h女强男视频 | 国产精品久久久久久久福利竹菊 | 成人午夜电影福利免费 | 久久久久久久国产免费看 | 国产精品福利在线观看免费不卡 | 国产色综合色产在线视频 | 国产精品久久久久久久久免费蜜桃 | 欧美精品中文字幕亚洲专区 | 免费一级欧美大片视频APP | 涩涩视频在线播放 | 99久久精品国产高清一区二区 | 胸大美女又黄的网站 | 亚洲国产女人aaa毛片在线 | 亚洲一级毛片免观看 | 国产福利萌白酱白色旗袍 | 少妇人妻AV毛片在线看 | 亚洲色欲国产综合久久天堂 | 亚裔美女被黑人巨大进入 | 国产真实露脸3p视频观看 | 丝袜另类在线观看网站 | 亚洲熟妇色自偷自拍另类 | 一本一道精品欧美中文字幕 | 国产精品酒店性爱视频 | 为您提供久久久久精品免费看 | 高潮又爽又大又黄无遮挡免费 |