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Rabbit Anti-METTL11A/Cy5 Conjugated antibody (bs-6057R-Cy5)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-6057R-Cy5
英文名稱 Rabbit Anti-METTL11A/Cy5 Conjugated antibody
中文名稱 Cy5標記的甲基化樣蛋白11抗體(N端)
別    名 Methyltransferase like 11A; Methyltransferase-like protein 11A; Mettl11a; N-terminal RCC1 methyltransferase; NRMT; NTM1A; NTM1A_HUMAN; NTMT1; X-Pro-Lys N-terminal protein methyltransferase 1A; AD 003; Alpha N-terminal protein methyltransferase 1A; C9orf32; Chromosome 9 open reading frame 32.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  免疫學  細胞周期蛋白  細胞分化  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse, Rat,  (predicted: Human, Chicken, Dog, Pig, Cow, Horse, )
產(chǎn)品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 25kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human METTL11A
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Alpha-N-methyltransferase that methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]-Pro-Lys when the initiator Met is cleaved. Specifically catalyzes mono-, di- or tri-methylation of exposed alpha-amino group of Ala, Pro or Ser residue in the [Ala/Pro/Ser]-Pro-Lys motif. Mediates the N-terminal methylation of KLHL31, MYL2, MYL3, RB1, RCC1, RPL23A and SET. Required during mitosis for normal bipolar spindle formation and chromosome segregation.

Function:
Alpha-N-methyltransferase that methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]-Pro-Lys when the initiator Met is cleaved. Specifically catalyzes mono-, di- or tri-methylation of exposed alpha-amino group of Ala or Ser residue in the [Ala/Ser]-Pro-Lys motif and mono- or di-methylation of Pro in the Pro-Pro-Lys motif. Responsible for the N-terminal methylation of KLHL31, MYL2, MYL3, RB1, RCC1, RPL23A and SET. Required during mitosis for normal bipolar spindle formation and chromosome segregation via its action on RCC1.

Subcellular Location:
Nucleus. Note=Predominantly nuclear.

Similarity:
Belongs to the methyltransferase superfamily. NTM1 family.

Database links:

Entrez Gene: 28989 Human

Entrez Gene: 66617 Mouse

Entrez Gene: 362103 Rat

Omim: 613560 Human

SwissProt: Q9BV86 Human

SwissProt: Q8R2U4 Mouse

SwissProt: Q5BJX0 Rat

Unigene: 522433 Human

Unigene: 33167 Mouse

Unigene: 12306 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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