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HRSP12 Rabbit pAb (bs-24087R)  
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產(chǎn)品編號 bs-24087R
英文名稱 HRSP12 Rabbit pAb
中文名稱 熱反應(yīng)蛋白12抗體
別    名 14.5 kDa translational inhibitor protein; Heat responsive protein 12; Heat-responsive protein 12; Hrsp12; p14.5; Perchloric acid soluble protein; PSP; Ribonuclease UK114; Translational inhibitor p14.5; Translational inhibitor protein p14.5; UK114; UK114 a  
研究領(lǐng)域 細(xì)胞生物  轉(zhuǎn)錄調(diào)節(jié)因子  結(jié)合蛋白  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 14 kDa
檢測分子量
細(xì)胞定位 細(xì)胞核 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse HRSP12: 51-135/135 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Endoribonuclease responsible for the inhibition of the translation by cleaving mRNA. Inhibits cell-free protein synthesis. Cleaves phosphodiester bonds only in single-stranded RNA.

Subcellular Location:
Cytoplasm. Nucleus. Mostly cytoplasmic but, in less differentiated cells occasionally nuclear.

Tissue Specificity:
Hepatocytes and renal distal tubular epithelial cells. Only weak expression in other tissues.

Similarity:
Belongs to the RutC family.

Database links:

Entrez Gene: 10247 Human

Entrez Gene: 15473 Mouse

Omim: 602487 Human

SwissProt: P52758 Human

SwissProt: P52760 Mouse

Unigene: 18426 Human



產(chǎn)品圖片
Paraformaldehyde-fixed, paraffin embedded (Mouse kidney); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (HRSP12) Polyclonal Antibody, Unconjugated (bs-24087R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
Paraformaldehyde-fixed, paraffin embedded (Mouse liver); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (HRSP12) Polyclonal Antibody, Unconjugated (bs-24087R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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