亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
日本欧美激情视频二区,91极品在线观看,国产AV无码专区毛片
首頁 > 產(chǎn)品中心 > 一抗 > 產(chǎn)品信息
SMAD5 Rabbit pAb (bs-13890R)  
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價

產(chǎn)品編號 bs-13890R
英文名稱 SMAD5 Rabbit pAb
中文名稱 細(xì)胞信號轉(zhuǎn)導(dǎo)分子SMAD5抗體
別    名 Dwfc; hSmad 5; hSmad5; JV5 1; JV5-1; MAD homolog 5; MAD mothers against decapentaplegic homolog 5; MAD, mothers against decapentaplegic homolog 5; MADH 5; MADH5; Mothers against decapentaplegic homolog 5; Mothers against DPP homolog 5; MusMLP; SMA and MAD related protein 5; SMAD 5; SMAD family member 5; SMAD mothers against DPP homolog 5; Smad5; SMAD5_HUMAN.  
Specific References  (2)     |     bs-13890R has been referenced in 2 publications.
[IF=4.966] Hui Luo. et al. miR‐130a promotes immature porcine Sertoli cell growth by activating SMAD5 through the TGF‐β‐PI3K/AKT signaling pathway. Faseb J. 2020 Nov;34(11):15164-15179  WB ;  Pig.  
[IF=2.784] Yang et al. miR-1307-3p suppresses the chondrogenic differentiation of human adipose-derived stem cells by targeting BMPR2. (2018) Int.J.Mol.Med. 42:3115-3124  WB ;  
研究領(lǐng)域 細(xì)胞生物  染色質(zhì)和核信號  信號轉(zhuǎn)導(dǎo)  干細(xì)胞  轉(zhuǎn)錄調(diào)節(jié)因子  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應(yīng) Human,Mouse (predicted: Rat,Rabbit,Pig,Sheep,Cow,Dog,GuineaPig)
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 51 kDa
檢測分子量
細(xì)胞定位 細(xì)胞核 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SMAD5: 151-250/465 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The protein encoded by this gene is involved in the transforming growth factor beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. The encoded protein is activated by bone morphogenetic proteins type 1 receptor kinase, and may be involved in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]

Function:
Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD5 is a receptor-regulated SMAD (R-SMAD).

Subunit:
May form trimers with the co-SMAD SMAD4. Interacts with PEBP2-alpha subunit and SMURF1. Interacts with SUV39H1 and SUV39H2. Interacts (via MH2 domain) with LEMD3. Interacts with WWP1.

Subcellular Location:
Cytoplasm. Nucleus. Cytoplasmic in the absence of ligand. Migrates to the nucleus when complexed with SMAD4.

Tissue Specificity:
Ubiquitous.

Post-translational modifications:
Phosphorylated on serine by BMP (bone morphogenetic proteins) type 1 receptor kinase.
Ubiquitin-mediated proteolysis by SMAD-specific E3 ubiquitin ligase SMURF1.

Similarity:
Belongs to the dwarfin/SMAD family.
Contains 1 MH1 (MAD homology 1) domain.
Contains 1 MH2 (MAD homology 2) domain.

SWISS:
Q99717

Gene ID:
4090

Database links:

Entrez Gene: 4090 Human

Entrez Gene: 17129 Mouse

Entrez Gene: 59328 Rat

Omim: 603110 Human

SwissProt: Q99717 Human

SwissProt: P97454 Mouse

SwissProt: Q9R1V3 Rat

Unigene: 167700 Human

Unigene: 272920 Mouse

Unigene: 146857 Rat



產(chǎn)品圖片
Sample: Testis (Mouse) Lysate at 40 ug Primary: Anti-SMAD5 (bs-13890R) at 1/500 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 51 kD Observed band size: 51 kD
Paraformaldehyde-fixed, paraffin embedded (mouse brain tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (SMAD5) Polyclonal Antibody, Unconjugated (bs-13890R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
HepG2 cell; 4% Paraformaldehyde-fixed; Triton X-100 at room temperature for 20 min; Blocking buffer (normal goat serum, C-0005) at 37°C for 20 min; Antibody incubation with (SMAD5) polyclonal Antibody, Unconjugated (bs-13890R) 1:100, 90 minutes at 37°C; followed by a conjugated Goat Anti-Rabbit IgG antibody at 37°C for 90 minutes, DAPI (blue, C02-04002) was used to stain the cell nuclei.
版權(quán)所有 2004-2026 a6308.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
加勒比色综合久久久久久久久 | 国产欧美一区二区三区不卡 | 伊人久久大香线蕉综合色狠狠 | 被CAO哭高H野外NP小说男男 | 成人免费的性色视频网站 | heyzo1754北岛玲在线视频 | 无码AV免费精品一区二区三区 | 51视频精品全部免费视频 | 日本XXXXX黄区免费看下载 | 被三个男人绑着躁我好爽 | 999国内精品永久免费视频 | 91精品久久久久久久久久 | 又爽又高潮的BB视频免费看 | 少妇的奶头又大又红又涨 | 91精品国产高清91久久久久久 | 亚洲AV无码专区在线观看 | 扒开双腿猛进入爽爽在线观看 | 黄色网站在线观看免费 | 国产免费看JIZZ视频 | 精品无码国产拍自产拍在线 | 男同桌上课时狂揉我下面污文 | 神马手机影院未来影院 | 又黄又湿免费高清视频 | 日本人爽p大片免费看 | 国产成人精品午夜福利在线播放 | 国产精品久久久久无码AV人妖 | 无遮挡国产高潮视频免费观看 | 人妻少妇精品无码专区二区 | 国产娱乐凹凸视觉盛宴在线视频 | 亚洲精品高清一二区久久 | 成人欧美一区二区三区白人 | 欧美日韩一区精品高免费专区 | 男人裸身露j不挡的图片 | 国精品无码人妻一区二区三区 | moneses性欧美| 99久久这里只精品国产免费 | 亚洲精品午夜久久久久久久久 | 久久久久精品国产亚洲av麻豆 | 四虎影视国产精品亚洲精品 | 91麻豆精品国产一级 | 精品国产成人亚洲午夜福利 |