| 產(chǎn)品編號 | bs-18285R |
| 英文名稱 | LINGO3 Rabbit pAb |
| 中文名稱 | 富含亮氨酸重復(fù)跨膜神經(jīng)元3抗體 |
| 別 名 | LINGO-3; hCG2040376; LERN2; Leucine rich repeat and Ig domain containing 3; Leucine rich repeat neuronal 6B; Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 3; Leucine-rich repeat neuronal protein 2; Leucine |
| 研究領(lǐng)域 | 細(xì)胞生物 神經(jīng)生物學(xué) 跨膜蛋白 細(xì)胞膜蛋白 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Pig,Cow,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 65 kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human LINGO3: 351-450/592 <Extracellular> |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Lingo-3 is a 592 amino acid single-pass type I membrane protein. Lingo-3 contains one immunoglobulin-like C2-type domain and fourteen leucine-rich repeats and is glycosylated at various positions during post-translational modification. Lingo-3 is expressed in a broad but specific pattern in many tissues across the embryo. The gene encoding Lingo-3 maps to to human chromosome 19p13.3 and mouse chromosome 10 C1. Chromosome 19 consists of approximately 63 million bases and makes up over 2% of human genomic DNA. Chromosome 19 is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin superfamily members including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family and Fc alpha receptors. Subcellular Location: Membrane. Similarity: Contains 1 Ig-like C2-type (immunoglobulin-like) domain. Contains 11 LRR (leucine-rich) repeats. Contains 1 LRRCT domain. Contains 1 LRRNT domain. SWISS: P0C6S8 Gene ID: 645191 Database links: Entrez Gene: 645191 Human Entrez Gene: 237403 Mouse Omim: 609792 Human SwissProt: P0C6S8 Human SwissProt: Q6GQU6 Mouse Unigene: 371587 Human Unigene: 40213 Mouse Unigene: 211966 Rat |
