亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號(hào)           掃碼咨詢(xún)技術(shù)支持           掃碼咨詢(xún)技術(shù)服務(wù)
  
客服熱線(xiàn):400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
chengrenwangzhan免费观看,亚洲一区精品在线,国产人成无码视频在线观看
首頁(yè) > 產(chǎn)品中心 > 一抗 > 產(chǎn)品信息
Activin Receptor Type IIB Rabbit pAb (bs-12417R)  
訂購(gòu)熱線(xiàn):400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢(xún)價(jià)

產(chǎn)品編號(hào) bs-12417R
英文名稱(chēng) Activin Receptor Type IIB Rabbit pAb
中文名稱(chēng) 激活素受體2B抗體
別    名 Activin Receptor Type IIB; ACTR-IIB; Activin A receptor type IIB; Activin receptor type 2B; Activin receptor type IIB; Activin receptor type-2B; ActR IIB; ACTR-IIB; ActRIIB; ACVR 2B; ACVR2B; AVR2B_HUMAN; HTX4; MGC116908.  
研究領(lǐng)域 細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  干細(xì)胞  生長(zhǎng)因子和激素  激酶和磷酸酶  細(xì)胞表面分子  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
克 隆 號(hào)
交叉反應(yīng) Human,Mouse,Rat (predicted: Pig,Sheep,Cow,Dog)
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 56 kDa
檢測(cè)分子量
細(xì)胞定位 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ACVR2B/ACTR-IIB: 45-150/512 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Members of the transforming growth factor b superfamily bind to a pair of transmembrane proteins, known as receptor types I and II, which contain serine/threonine kinases and associate to form a signaling complex (1). Activin has been shown to bind a heteromeric noncovalent complex, which consists of a type I receptor, ACTR-IA (also designated ACVRI and ALK-2) or ACTR-IB (also designated ALK-4 and SKR2), and a type II receptor, ACTR-IIA (also designated ACVR2A) or ACTR-IIB (also designated ACVR2B) (1-6). Both receptor types are highly expressed in brain (5). The activin receptor family members are thought to mediate distinct effects on gene expression, cell differentiation, and morpho- genesis in a dose dependent fashion (5,6).

Function:
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A.

Subunit:
Forms an activin receptor complex with activin type II receptors such as ACVR1B. Interacts with VPS39.

Subcellular Location:
Cell membrane; Single-pass type I membrane protein.

Post-translational modifications:
Phosphorylated. Constitutive phosphorylation is in part catalyzed by its own kinase activity.

DISEASE:
Defects in ACVR2B are the cause of visceral heterotaxy autosomal type 4 (HTX4) [MIM:613751]. A form of visceral heterotaxy, a complex disorder due to disruption of the normal left-right asymmetry of the thoracoabdominal organs. It results in an abnormal arrangement of visceral organs, and a wide variety of congenital defects. Clinical features of visceral heterotaxy type 4 include dextrocardia, right aortic arch and a right-sided spleen, anomalies of the inferior and the superior vena cava, atrial ventricular canal defect with dextro-transposed great arteries, pulmonary stenosis, polysplenia and midline liver.

Similarity:
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.
TGFB receptor subfamily.
Contains 1 protein kinase domain.

SWISS:
Q13705

Gene ID:
93

Database links:

Entrez Gene: 93 Human

Entrez Gene: 11481 Mouse

Entrez Gene: 25366 Rat

Omim: 602730 Human

SwissProt: Q13705 Human

SwissProt: P27040 Mouse

SwissProt: P38445 Rat

Unigene: 174273 Human

Unigene: 390239 Mouse

Unigene: 24240 Rat



產(chǎn)品圖片
Sample: Lane 1: Mouse Heart tissue lysates Lane 2: Mouse Muscle tissue lysates Lane 3: Mouse Testis tissue lysates Lane 4: Mouse Kidney tissue lysates Lane 5: Human K562 cell lysates Lane 6: Human SH-SY5Y cell lysates Lane 7: Human Jurkat cell lysates Lane 8: Human MOLT4 cell lysates Primary: Anti-Activin Receptor Type IIB (bs-12417R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 56 kDa Observed band size: 60 kDa
Sample: K562(Human) Cell Lysate at 30 ug 293T(Human) Cell Lysate at 30 ug Primary: Anti- Activin Receptor Type IIB (bs-12417R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 56 kD Observed band size: 56 kD
Paraformaldehyde-fixed, paraffin embedded (Human kidney); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Activin Receptor Type IIB) Polyclonal Antibody, Unconjugated (bs-12417R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
版權(quán)所有 2004-2026 a6308.cn 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書(shū)編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書(shū)編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
三级毛片在线播放 | 欧美黑人xxxxww| 狠狠综合久久综合88亚洲 | 国产第一页浮力影院草草影视 | 国产一区二区无码中文 | 精品一区二区三区高清免费观看 | 人妻少妇精品久久久久久0000 | 欧美日韩一级久久久久久免费看 | 国产小视频在线高清播放 | 国产一级特黄A片高潮片 | 亚洲线精品一区二区三区八戒 | 无码区国产区在线播放 | 啊灬啊灬啊灬快灬高潮了听书 | 被三个男人绑着躁我好爽 | 婷婷五月综合缴情在线视频 | 日韩欧美亚洲每日更新在线 | 国产成人自产拍免费视频 | 两根硕大一起挤进小紧H共妻 | 午夜欧美日韩国产福利91不卡一区二区三区 | 三级日本高清完整版热播 | 日本精品一区二区三区高清 | 日韩亚洲人成网站在线播放 | 色欲精品人妻AV一区二区三区 | 最近免费中文字幕大全高清大全1 | 免费国产一级片内射视频 | 国产主播福利一区二区 | 91精品国自产在线观看 | chinese强制吹潮男男视频 | 精品一区二区三区在线成人 | 在线永久看片免费的视频 | 快插我BB好爽舔我视频 | 特级做a爰片毛片免费看 | 亚洲中文字幕无码一久久区 | 亚洲精品初高中精品久久自慰网站 | AV无码免费一区二区三区不卡 | 国产69精品久久久久APP下载 | 国产一区二区三区水蜜桃 | 婷婷六月激情综合一区 | 亚洲无人区码一二三码区别图片 | 我们日本在线观看免费动漫下载 | 国产猛男猛女超爽免费视频 |