亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號(hào)           掃碼咨詢(xún)技術(shù)支持           掃碼咨詢(xún)技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
日本三级电影在线看,久久香蕉综合一本到3atv
首頁(yè) > 產(chǎn)品中心 > 一抗 > 產(chǎn)品信息
MAL2 Rabbit pAb (bs-7175R)  
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢(xún)價(jià)

產(chǎn)品編號(hào) bs-7175R
英文名稱(chēng) MAL2 Rabbit pAb
中文名稱(chēng) T淋巴細(xì)胞分化蛋白MAL2抗體
別    名 MAL 2; MAL proteolipid protein 2; Mal, T cell differentiation protein 2; mal2; MAL2_HUMAN; Protein MAL2.  
Specific References  (3)     |     bs-7175R has been referenced in 3 publications.
[IF=9.423] Jaekwang Jeong. et al. MAL2 mediates the formation of stable HER2 signaling complexes within lipid raft-rich membrane protrusions in breast cancer cells. Cell Rep. 2021 Dec;37:110160  IF ;  Human.  
[IF=7.919] Le Tao. et al. FTO modifies the m6A level of MALAT and promotes bladder cancer progression. Clin Transl Med. 2021 Feb;11(2):e310  IHC ;  Human.  
[IF=5.875] Feiyang Deng. et al. Lipid raft-mediated and upregulated coordination pathways assist transport of glycocholic acid-modified nanoparticle in a human breast cancer cell line of SK-BR-3. Int J Pharmaceut. 2022 Apr;617:121589  IF ;  Human.  
研究領(lǐng)域 腫瘤  細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞分化  淋巴細(xì)胞  新陳代謝  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
克 隆 號(hào)
交叉反應(yīng) Human (predicted: Mouse,Rat,Pig,Cow)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 19 kDa
檢測(cè)分子量
細(xì)胞定位 細(xì)胞漿 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MAL2: 21-120/176 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The MARVEL domain is a 130 amino acid motif that contains four transmembrane helices, both of which have cytoplasmic N- and C-terminal regions. MARVEL domain-containing proteins are thought to participate in tight junction regulation, the biogenesis of vesicular transport carriers and in cholesterol-rich membrane apposition events. MAL2 (mal, T-cell differentiation protein 2) is a 176 amino acid multi-pass membrane protein that is associated with lipid rafts and contains one MARVEL domain. Expressed predominately in liver, kidney and lung, MAL2 functions as a member of the polarized machinery transport system and is required for transcytosis, a transporter pathway used to deliver membrane-bound cargo from perinuclear endosomes to the apical surface in a raft-dependent manner. Differential expression of MAL2 is associated with several cancers, including renal cell carcinoma and childhood leukemia, suggesting a role for MAL2 in tumorigensis.

Function:
Member of the machinery of polarized transport. Required for the indirect transcytotic route at the step of the egress of the transcytosing cargo from perinuclear endosomes in order for it to travel to the apical surface via a raft-dependent pathway.

Subunit:
Interacts with TPD52L2.

Subcellular Location:
Cell membrane. Apical cell membrane. Endomembrane system. Cytoplasm > perinuclear region. Associated with lipid rafts. In polarized epithelial cells, restricted to the apical surface. In hepatocytes, as well as in polarized hepatoma HepG2 cells, found in the canalicular membrane, equivalent to the apical surface, beneath the canalicular actin cytoskeleton. In non-polarized HepG2 cells, distributed to the perinuclear region.

Tissue Specificity:
Predominantly expressed in kidney, lung, and liver. Also found in thyroid gland, stomach and, at lower levels in testis and small intestine.

Similarity:
Belongs to the MAL family.
Contains 1 MARVEL domain.

SWISS:
Q969L2

Gene ID:
114569

Database links:

Entrez Gene: 114569 Human

Entrez Gene: 105853 Mouse

Entrez Gene: 362911 Rat

Omim: 609684 Human

SwissProt: Q969L2 Human

SwissProt: Q8BI08 Mouse

Unigene: 201083 Human

Unigene: 410994 Mouse



產(chǎn)品圖片
Paraformaldehyde-fixed, paraffin embedded (human liver carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (MAL2) Polyclonal Antibody, Unconjugated (bs-7175R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
版權(quán)所有 2004-2026 a6308.cn 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書(shū)編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書(shū)編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
国产午夜人做人免费视频APP | 51视频精品全部免费视频 | 亚洲 日韩 丝袜 熟女 变态 | 免费永久在线观看黄网 | 国内久经典AAAAA片 | 全部在线播放免费毛片 | 男人女人爽好猛好痛视频 | 欧美午夜精品久久久久久浪潮 | 91热成人精品国产免费 | 377人体粉嫩噜噜噜 高清欧美性猛交xxxx黑人猛交 | 伊人久久综合精品无码av专区 | 成年片色大黄全免费网站观看 | 少妇人妻一级A毛片无码 | 免费在线观看一区 | 国产精品三P一区二区视频 最近高清中文字幕免费MV | 亚洲人成色777777在线观看 | 国产一区二区三区AV天堂 | 欧美人与黑人牲交全过程视 | 97色伦图片97色伦图影院久久 | 综合久久狠狠色99h中午 | 欧美精品久久久久久久小说 | 一本—道久久a久久精品蜜桃 | 妇女BBBB插插插视频 | 日韩视频在线精品视频免费观看 | 国产制服91一区二区三区制服 | 少妇荡乳情欲办公室456视频 | 麻豆国产精品番甜甜七夕 | 艳妇臀荡乳欲伦69调教视频 | 短篇公交车高H肉辣全集目录 | 狠狠做深爱婷婷久久综合一区 | 一级a性色生活片久久无码火 | 亚洲欧美一区二区三区导航 | 美一女一无一伦一精一品 | 国内精品51视频在线观看 | 人妻无码熟妇乱又伦精品 | 少妇被躁爽到高潮无码麻豆AV | 欧美成人精品视频在线播放 | AV毛片无码乱码国产精品 | 成人毛片100免费观看 | 奇米综合四色77777久久 | 国产大屁股喷水视频在线 |