亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
欧美精品一区二区蜜臀亚洲,久久久久久久久久国产精品免费,日欧137片内射在线视频播放
首頁 > 產(chǎn)品中心 > 一抗 > 產(chǎn)品信息
SARM1 Rabbit pAb (bs-9001R)  
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價

產(chǎn)品編號 bs-9001R
英文名稱 SARM1 Rabbit pAb
中文名稱 SARM蛋白抗體
別    名 FLJ36296; KIAA0524; MyD88-5; SAM and ARM-containing protein; SAM domain-containing protein 2; SAMD2; SARM 1; SARM1; SARM1_HUMAN; Sterile alpha and Armadillo repeat protein; sterile alpha and HEAT/Armadillo motif protein, ortholog of Drosophila; sterile alpha and HEAT/Armadillo motifs-containing protein; sterile alpha and TIR motif containing 1; Sterile alpha and TIR motif-containing protein 1; Sterile alpha and TIR motifs-containing protein 1; Sterile alpha motif domain-containing protein 2; Tir-1 homolog.  
Specific References  (1)     |     bs-9001R has been referenced in 1 publications.
[IF=2.992] Cuiqin Zhang. et al. Atg7 Knockout Alleviated the Axonal Injury of Neuro-2a Cells Induced by Tri-Ortho-Cresyl Phosphate. 2021 Mar 01  WB ;  Mouse.  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  信號轉(zhuǎn)導(dǎo)  生長因子和激素  淋巴細(xì)胞  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應(yīng) Human (predicted: Mouse,Rat,Rabbit,Pig,Cow,Dog,Horse)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 80 kDa
檢測分子量
細(xì)胞定位 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SARM1: 321-420/724 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 SARM, also known as SAMD2, SARM1 or KIAA0524, is a 724 amino acid protein that localizes to the cytoplasm and contains one TIR domain and two sterile alpha motif (SAM) domains. Expressed predominately in liver and kidney and present at lower levels in placenta, SARM interacts with TICAM-1 and, via this interaction, blocks the transcriptional activation activity of TICAM-1 and functions as a negative regulator of Toll-like receptor signaling. Additionally, SARM is thought to be involved in innate immune responses and may also play a role in the negative regulation of NFⅹB activation. SARM exists as two alternatively spliced isoforms that are encoded by a gene which maps to human chromosome 17.

Function:
Involved in innate immnune response. Acts as a negative regulator of TICAM1/TRIF-dependent Toll-like receptor signaling by inhibiting induction of TLR3- and TLR4-dependent genes. Specifically blocks TICAM1/TRIF-dependent transcription-factor activation and gene induction, without affecting the MYD88-dependent pathway or non-TLR signaling. Negative regulator of NF-kappa-B and IRF activation.

Subunit:
Interacts with TICAM1/TRIF and thereby interferes with TICAM1/TRIF function.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Predominantly expressed in kidney and liver. Expressed at lower level in placenta.

Similarity:
Contains 2 SAM (sterile alpha motif) domains.
Contains 1 TIR domain.

SWISS:
Q6SZW1

Gene ID:
23098

Database links:

Entrez Gene: 23098 Human

Entrez Gene: 237868 Mouse

Omim: 607732 Human

SwissProt: Q6SZW1 Human

SwissProt: Q6PDS3 Mouse

Unigene: 446689 Human

Unigene: 743510 Human

Unigene: 210332 Mouse



產(chǎn)品圖片
Paraformaldehyde-fixed, paraffin embedded (Human liver tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (SARM1) Polyclonal Antibody, Unconjugated (bs-9001R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
版權(quán)所有 2004-2026 a6308.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
丁香花在线影院观看在线播放 | 欧美最猛黑人XXXXWWW | 国产美女视频一区二区二三区 | 国产亚洲美日韩AV中文字幕无码成人 | 国产一级一片免费播放i | 无码的免费不卡毛片视频 | 久久久精品国产亚州AV水蜜桃 | 一级做a爰片久久毛片免费陪 | 欧美午夜一区二区福利视频 | 换脸国产AV一区二区三区 | 亚洲精品ty久久久久久久久久 | 天堂8中文在线最新版官网 91日本在线视频 | 任你躁在线精品免费 | 无码不卡免费v片在线观看 国产未发育呦交视频 | a级毛片黄免费a级毛片 | 精品久久久久中文字幕日本 | 欧美一区二区三区免费视频 | 欧美一区二区视频在线观看 | 寡妇高潮一级毛片免费看 | 米奇奇米777第四色 国产精品免费大片 | 久久亚洲精品国产亚洲老地址 | 欧美日韩激情综合一区二区不卡 | 最近中文字幕mv免费高清在线视频 | 四虎一区二区成人免费影院网址 | 久久五月丁香激情综合 | 亚洲精品国产综合久久一线 | 日韩欧美一区二区三区免费观看 | 免费一级做a爰片久久毛片潮喷 | 一本一道久久a久久综合蜜桃 | 国产人成一区二区三区影院 | 女性高爱潮AAAA级视频免费 | 国精产品999一区二区三区有限 | 国产精品免费一区二区三区四区 | 国产成人精品电影在线观看 | 在线观看亚洲一区二区 | 国产精品久久综合桃花网 | 四虎一区二区成人免费影院网址 | 欧美综合自拍亚洲综合百度 | 日本一区二区三区在线网 | 国产AV一区二区三区天堂综合网 | 亚洲韩欧美第25集完整版 |